Lack of antibody induction by Histolyn-CYL, a new skin-testing reagent for histoplasmosis.

Abstract

Histolyn-CYL, a yeast phase skin-test reagent, was administered to 85 histoplasmin-sensitive subjects living in the United States and South America. In a multicenter study, sera were obtained at the time the skin tests were read and again 3 weeks later. In no instance did the skin test induce significant complement-fixing antibody changes or antibodies detected by immuno-diffusion.

• Authors: G M Scalarone, A Restrepo, L R Schacht, G H Rupp, M D LeRoy
• Journal: Sabouraudia (Sabouraudia) Vol. 23 Issue 5 Pg. 335-8 (Oct 1985) ISSN: 0036-2174 [Print] England
• PMID: 3934772 (Publication Type: Journal Article)

Chemical References

• Antigens, Fungal
• histolyn CYL
• Histoplasmin

Topics

• Adult
• Antigen-Antibody Reactions
• Antigens, Fungal
• California
• Colombia
• Complement Fixation Tests
• Histoplasmin
• Histoplasmosis (diagnosis, immunology)
• Humans
• Immunodiffusion
• Ohio
• Skin Tests (methods)