[Chronic lymphocytic leukemia, erythroblastopenia, thymolipoma].

Abstract

The association of B cell chronic lymphocytic leukemia and pure red cell aplasia in a 42 year-old patient led to the discovery of a thymic enlargement. After six weeks treatment including steroids, cyclophosphamide and three courses of plasma exchange without improvement, surgical thymectomy was followed by a reticulocytosis and remission of the red cell aplasia. The tumor was a thymolipoma. Characteristics of this are thymic tumor, his connections with pure red cell aplasia and in vitro differentiation of erythroid progenitors are discussed.

• Authors: E Lebrun, F Ajchenbaum, X Troussard, F Galateau, M Leporrier, C Lacombe, N Casadevall, B Varet, J P Vernant, J Dumont
• Journal: Nouvelle revue francaise d'hematologie (Nouv Rev Fr Hematol (1978)) Vol. 27 Issue 1 Pg. 29-37 ( 1985) Germany
• Vernacular Title: Leucémie lymphoïde chronique, érythroblastopénie, thymolipome.
• PMID: 3921941 (Publication Type: Case Reports, English Abstract, Journal Article)

Chemical References

• Antineoplastic Agents

Topics

• Adult
• Antineoplastic Agents (therapeutic use)
• Humans
• Leukemia, Lymphoid (complications, drug therapy)
• Lipoma (complications, surgery)
• Male
• Red-Cell Aplasia, Pure (complications, therapy)
• Thymus Neoplasms (complications, surgery)