Antibiotic prophylaxis for major maxillocraniofacial surgery.

Abstract

A shortened prophylactic regimen of antibiotics for maxillofacial and craniofacial surgery is evaluated. Eighty-five patients were divided into two groups on the basis of the type of incision used. Forty-nine patients undergoing intraoral procedures received penicillin perioperatively and were given one postoperative dose (regimen A). Thirty-six patients undergoing extraoral or combined intraoral and extraoral procedures received penicillin and oxacillin perioperatively, with nine receiving one postoperative dose and 27 receiving an average of seven postoperative doses (regimen B). One infection was observed in the regimen A group, and three were observed in the regimen B group. This infection rate compares favorably to that encountered in the authors' previously reported study on longer prophylactic courses of antibiotics.

• Authors: M A Conover, L B Kaban, J B Mulliken
• Journal: Journal of oral and maxillofacial surgery : official journal of the American Association of Oral and Maxillofacial Surgeons (J Oral Maxillofac Surg) Vol. 43 Issue 11 Pg. 865-9 (Nov 1985) ISSN: 0278-2391 [Print] United States
• PMID: 3903082 (Publication Type: Journal Article)

Chemical References

• Clindamycin
• Penicillin G
• Oxacillin

Topics

• Adolescent
• Adult
• Bacteria (isolation & purification)
• Bone Transplantation
• Child
• Clindamycin (administration & dosage, therapeutic use)
• Facial Bones (surgery)
• Humans
• Injections, Intravenous
• Orthognathic Surgical Procedures
• Osteotomy
• Oxacillin (administration & dosage, therapeutic use)
• Penicillin G (administration & dosage, therapeutic use)
• Penicillin Resistance
• Surgical Wound Infection (etiology, microbiology)