Abstract |
Specific immunity against Yersinia was induced by plasmid-encoded antigens not associated with virulence. Mice were immunised with viable bacteria from a virulence-plasmid-cured strain of Y. pseudotuberculosis. This antigenic stimulation generated specific protection against virulence-plasmid-harbouring strains of Y. pseudotuberculosis and Y. pestis, demonstrating that protection can be generated by organisms lacking plasmid-encoded virulence antigens.
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Authors | M Simonet, P Berche, D Mazigh, M Veron |
Journal | Journal of medical microbiology
(J Med Microbiol)
Vol. 20
Issue 2
Pg. 225-31
(Oct 1985)
ISSN: 0022-2615 [Print] England |
PMID | 3900406
(Publication Type: Journal Article)
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Chemical References |
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Topics |
- Animals
- Antigens, Bacterial
(genetics, immunology)
- Female
- Immunity, Active
- Immunization
- Listeriosis
(immunology, microbiology)
- Mice
- Mice, Inbred ICR
- Plague
(immunology, microbiology)
- Plasmids
- Spleen
(microbiology)
- Virulence
- Yersinia
(genetics, growth & development, immunology, pathogenicity)
- Yersinia Infections
(immunology, microbiology)
- Yersinia enterocolitica
(growth & development, immunology)
- Yersinia pestis
(growth & development, immunology)
- Yersinia pseudotuberculosis Infections
(immunology, microbiology)
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