Hyperinsulinemia in acute intermittent porphyria.

Abstract

Diabetic oral glucose tolerance test together with hyperinsulinemia in a patient with decompensated acute intermittent porphyria is contrasted to normal findings in compensated acute intermittent porphyria (AIP). Results point to the essential role of insulin for the depression of porphyrin precursor overproduction as a mediator of the "glucose effect".

• Authors: F Sixel-Dietrich, F Verspohl, M Doss
• Journal: Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et metabolisme (Horm Metab Res) Vol. 17 Issue 7 Pg. 375-6 (Jul 1985) ISSN: 0018-5043 [Print] Germany
• PMID: 3897010 (Publication Type: Journal Article, Research Support, Non-U.S. Gov't)

Chemical References

• Insulin
• Porphobilinogen
• Aminolevulinic Acid

Topics

• Acute Disease
• Adolescent
• Adult
• Aminolevulinic Acid (urine)
• Female
• Glucose Tolerance Test
• Humans
• Hyperinsulinism (blood, complications)
• Insulin (blood)
• Liver Diseases (blood, complications)
• Porphobilinogen (blood)
• Porphyrias (blood, complications)