A double-blind comparison of clebopride and placebo in dyspepsia secondary to delayed gastric emptying.

Abstract

Seventy-six patients suffering from dyspeptic symptoms secondary to roentgenologically demonstrated delayed gastric emptying were treated with clebopride (0.5 mg TID) or with placebo during a three-month double-blind trial. Clebopride was more effective (P less than or equal to 0.001) than placebo in reducing or relieving symptoms and roentgenological findings associated with delayed gastric emptying. No interactions of clebopride with concomitant drugs or coexisting disorders were observed, and the incidence of side effects was low. We conclude that clebopride will be beneficial in the management of patients with delayed gastric emptying.

• Authors: L Bavestrello, L Caimi, A Barbera
• Journal: Clinical therapeutics (Clin Ther) Vol. 7 Issue 4 Pg. 468-73 ( 1985) ISSN: 0149-2918 [Print] United States
• PMID: 3893703 (Publication Type: Clinical Trial, Comparative Study, Controlled Clinical Trial, Journal Article)

Chemical References

• Antiemetics
• Benzamides
• clebopride

Topics

• Adolescent
• Adult
• Aged
• Antiemetics (adverse effects, therapeutic use)
• Benzamides (adverse effects, therapeutic use)
• Clinical Trials as Topic
• Double-Blind Method
• Dyspepsia (drug therapy, etiology)
• Female
• Gastric Emptying (drug effects)
• Humans
• Male
• Middle Aged
• Random Allocation