Analgesic effect of ceruletide compared with pentazocine in biliary and renal colic: a prospective, controlled, double-blind study.

Abstract

The analgesic effect of ceruletide in biliary and renal colic was evaluated by a randomized, double-blind study in 82 patients. Ceruletide was compared with pentazocine, a well-established analgetic agent. Rapid and effective analgesia was obtained by intramuscular injection of ceruletide 0.5 micrograms/kg in 56 patients with biliary colic. The analgesic effect of ceruletide compared well with pentazocine 0.5 mg/kg im, and was associated with remarkably fewer side effects. In 26 patients with renal colic, ceruletide was significantly inferior to pentazocine. These data support the recommendation of ceruletide as a first-choice analgetic agent for biliary colic.

• Authors: M Lishner, R Lang, I Jutrin, C De-Paolis, M Ravid
• Journal: Drug intelligence & clinical pharmacy (Drug Intell Clin Pharm) Vol. 19 Issue 6 Pg. 433-6 (Jun 1985) ISSN: 0012-6578 [Print] United States
• PMID: 3891284 (Publication Type: Clinical Trial, Comparative Study, Journal Article, Randomized Controlled Trial)

Chemical References

• Ceruletide
• Pentazocine

Topics

• Adult
• Biliary Tract Diseases (drug therapy)
• Ceruletide (therapeutic use)
• Clinical Trials as Topic
• Colic (drug therapy)
• Double-Blind Method
• Female
• Humans
• Kidney Diseases (drug therapy)
• Male
• Middle Aged
• Pentazocine (therapeutic use)
• Random Allocation
• Time Factors