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[Acquired immunodeficiency syndrome in a child of Swiss origin whose mother died from AIDS].

Abstract
Report of a now 2 8/12-year-old girl, who presented at the age of 8 months with chronic progressive pneumonia, mucocutaneous candidiasis, diarrhea, failure to thrive and a non-progressive paraplegia. The child's mother presented AIDS with pneumocystis carinii pneumonia and progressive general paralysis one year after the beginning of the child's disease and died within a few months. Additional findings in the child include lymphopenia, hyperimmunoglobulinemia, cutaneous anergy and an abnormal T helper/T suppressor cell ratio. HTLV-III antibodies were positive (ELISA and Western blot virus strip RIA). Prophylactic treatment with Co-trimoxazole relieved pulmonary infections but failure to thrive remained unchanged in spite of a continuous nutritional support. A vertical mode of transmission of AIDS from mother to child seems very probable.
AuthorsA Bircher, H I Joller-Jemelka, P W Joller, S Rampini, M Vogt, D H Shmerling, J Briner, J Schüpbach
JournalHelvetica paediatrica acta (Helv Paediatr Acta) Vol. 40 Issue 4 Pg. 261-76 (Sep 1985) ISSN: 0018-022X [Print] Switzerland
Vernacular TitleErworbenes Immunmangelsyndrom bei einem Kind schweizerischer Abstammung, dessen Mutter an AIDS verstorben ist.
PMID3878345 (Publication Type: Case Reports, English Abstract, Journal Article)
Topics
  • Acquired Immunodeficiency Syndrome (complications, transmission)
  • Child, Preschool
  • Failure to Thrive (etiology)
  • Female
  • Humans
  • Leukoencephalopathy, Progressive Multifocal (etiology)
  • Pneumonia, Pneumocystis (etiology)
  • Prognosis
  • Radiography, Thoracic
  • Respiratory Tract Infections (etiology)

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