Abstract |
Three patients with acute lymphoblastic leukemia (ALL) and heterozygous for the Mediterranean variant of glucose-6-phosphate dehydrogenase (G6PD) have been investigated with the 2-deoxyglucose-6-phosphate (2dG6P) method to determine the number and type of progenitor cells in which the disease arose. A monoclonal origin was established for the lymphoblasts, while the other hemopoietic cell lines were not involved in the leukemic process.
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Authors | A M Ferraris, L Canepa, L Massimo, G Dini, G Broccia, T Meloni, G Forteleoni, C Melani, G F Gaetani |
Journal | American journal of hematology
(Am J Hematol)
Vol. 20
Issue 1
Pg. 81-3
(Sep 1985)
ISSN: 0361-8609 [Print] United States |
PMID | 3861091
(Publication Type: Case Reports, Journal Article, Research Support, Non-U.S. Gov't)
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Chemical References |
- Deoxyglucose
- Glucosephosphate Dehydrogenase
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Topics |
- Child
- Child, Preschool
- Deoxyglucose
(metabolism)
- Female
- Glucosephosphate Dehydrogenase
(genetics)
- Heterozygote
- Humans
- Leukemia, Lymphoid
(genetics)
- Middle Aged
- Neoplastic Stem Cells
- Stem Cells
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