[Clinical evaluation of cefmenoxime (CMX) for complicated urinary tract infection].

Abstract

Cefmenoxime (CMX), a new semisynthetic antibiotic, was administrated in 29 cases diagnosed as complicated urinary tract infection. All patients received drip injection of 2 g (twice a day) for 5 days. Clinical results were excellent in 1 patient (3.4%), good in 15 patients (51.8%) and poor in 13 patients (44.8%). Effectiveness rate was 55.2%. In bacteriological response, out of 35 strains 27 (77.1%) strains were eradicated and 8 (22.9%) strains persisted. As for side effects, except one case of transient diarrhea after administration, no noteworthy reactions were observed. Laboratory abnormalities attributed to CMX treatment consisted of 4 cases of elevated serum transaminase and 2 cases of elevated serum creatinine.

• Authors: S Tsuchida, S Sasaki, H Takada, S Miyagata, S Sato, S Shimizu, F Sakamoto, N Kizu
• Journal: Hinyokika kiyo. Acta urologica Japonica (Hinyokika Kiyo) Vol. 31 Issue 2 Pg. 365-74 (Feb 1985) ISSN: 0018-1994 [Print] Japan
• PMID: 3859998 (Publication Type: English Abstract, Journal Article)

Chemical References

• Cefmenoxime
• Cefotaxime

Topics

• Adult
• Aged
• Bacteria (isolation & purification)
• Cefmenoxime
• Cefotaxime (administration & dosage, adverse effects, analogs & derivatives, therapeutic use)
• Drug Evaluation
• Female
• Humans
• Male
• Middle Aged
• Urinary Tract Infections (drug therapy, microbiology)