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[Clinical experience with aspoxicillin in the pediatric field].

Abstract
Aspoxicillin (TA-058, ASPC) was given intravenously to 20 children with the following acute bacterial infections; 11 cases of bronchopneumonia, 5 cases of urinary tract infection, 2 cases of acute bronchitis, 1 case of staphylococcal scalded skin syndrome and 1 case of subcutaneous abscess. Clinical effectiveness was obtained in 14 cases out of 20 cases (70%) and bacteriological eradication in 8 cases out of 10 cases (80%). With ASPC the following side effects developed; transient diarrhea in 1 case, eruption in 1 case and slight elevation of GOT in 1 case. From the above clinical results, it is apparent that ASPC is an useful antibiotic for treating pediatric patients with various kinds of bacterial infections.
AuthorsH Kobashi, A Nishioka, N Miyamoto, K Oohara, T Okamoto
JournalThe Japanese journal of antibiotics (Jpn J Antibiot) Vol. 38 Issue 7 Pg. 1911-7 (Jul 1985) ISSN: 0368-2781 [Print] Japan
PMID3851863 (Publication Type: English Abstract, Journal Article)
Chemical References
  • aspoxicillin
  • Amoxicillin
Topics
  • Amoxicillin (administration & dosage, analogs & derivatives, pharmacology, therapeutic use)
  • Bacteria (drug effects)
  • Bacterial Infections (drug therapy)
  • Bronchitis (drug therapy)
  • Bronchopneumonia (drug therapy)
  • Child
  • Child, Preschool
  • Drug Evaluation
  • Female
  • Humans
  • Infant
  • Infusions, Parenteral
  • Injections, Intravenous
  • Male
  • Penicillin Resistance
  • Urinary Tract Infections (drug therapy)

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