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Importance of diet of dam and colostrum to the biological antioxidant status and parenteral iron tolerance of the pig.

Abstract
Fifteen second-parity sows were used to determine the importance of vitamin E (E) and selenium (Se) supplementation of the sow's diet and colostrum consumption by the neonatal pig on tolerance to parenteral iron. Selenium (.1 ppm) and E (50 IU/kg) supplementation of the diet of the sow increased plasma tocopherol and Se concentrations, but did not increase plasma glutathione peroxidase (GSH-Px) activity. Colostrum had greater concentrations of E (primarily alpha-tocopherol) and Se than milk. Plasma biological antioxidant status (tocopherol level and GSH-Px activity) of pigs at birth was very low, but by 2 d of age had increased, especially in alpha-tocopherol (nearly a 20-fold increase). Liveability and body weight gain of pigs were not affected by the pre-colostrum iron injection (200 mg Fe as gleptoferron); however, plasma tocopherol concentrations of Fe-injected pigs were lower and plasma Se concentration and GSH-Px activities were higher at 2 d of age than values of pigs not receiving parenteral Fe. Supplementation of the dam's diet with E and Se maintained high tocopherol and Se levels in her colostrum and milk and a high biological antioxidant status in her pigs throughout the nursing period.
AuthorsM J Loudenslager, P K Ku, P A Whetter, D E Ullrey, C K Whitehair, H D Stowe, E R Miller
JournalJournal of animal science (J Anim Sci) Vol. 63 Issue 6 Pg. 1905-14 (Dec 1986) ISSN: 0021-8812 [Print] United States
PMID3818467 (Publication Type: Journal Article)
Chemical References
  • Vitamin E
  • Iron
  • Selenious Acid
  • alpha-Tocopherol
  • Selenium
  • Tocopherols
Topics
  • Animals
  • Animals, Newborn (blood)
  • Chromatography, High Pressure Liquid
  • Colostrum (analysis)
  • Female
  • Iron (pharmacology)
  • Milk (analysis)
  • Pregnancy
  • Selenious Acid
  • Selenium (blood, pharmacology)
  • Swine (blood)
  • Tocopherols
  • Vitamin E (analogs & derivatives, blood, pharmacology)
  • alpha-Tocopherol (analogs & derivatives)

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