Abstract |
A clinical study was conducted on the effects of an alexidine or placebo oral rinse on plaque and gingivitis. Forty-two male subjects rinsed for 54 days while continuing toothbrushing. This was followed by 4 days of mouthrinsing only. The alexidine mouthrinse significantly reduced the plaque index when used in conjunction with toothbrushing and also when brushing was discontinued. The gingivitis results were inconclusive.
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Authors | A J Formicola, M J Deasy, O E Graessle, D H Johnson, E E Howe |
Journal | Journal of periodontology
(J Periodontol)
Vol. 49
Issue 3
Pg. 145-7
(Mar 1978)
ISSN: 0022-3492 [Print] United States |
PMID | 381628
(Publication Type: Clinical Trial, Controlled Clinical Trial, Journal Article)
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Chemical References |
- Biguanides
- Mouthwashes
- Placebos
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Topics |
- Adult
- Biguanides
(therapeutic use)
- Clinical Trials as Topic
- Dental Plaque
(prevention & control)
- Double-Blind Method
- Drug Evaluation
- Gingivitis
(prevention & control)
- Humans
- Male
- Middle Aged
- Mouthwashes
(therapeutic use)
- Oral Hygiene
- Placebos
- Toothbrushing
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