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The effect of an alexidine mouthwash on plaque and gingivitis.

Abstract
A clinical study was conducted on the effects of an alexidine or placebo oral rinse on plaque and gingivitis. Forty-two male subjects rinsed for 54 days while continuing toothbrushing. This was followed by 4 days of mouthrinsing only. The alexidine mouthrinse significantly reduced the plaque index when used in conjunction with toothbrushing and also when brushing was discontinued. The gingivitis results were inconclusive.
AuthorsA J Formicola, M J Deasy, O E Graessle, D H Johnson, E E Howe
JournalJournal of periodontology (J Periodontol) Vol. 49 Issue 3 Pg. 145-7 (Mar 1978) ISSN: 0022-3492 [Print] United States
PMID381628 (Publication Type: Clinical Trial, Controlled Clinical Trial, Journal Article)
Chemical References
  • Biguanides
  • Mouthwashes
  • Placebos
Topics
  • Adult
  • Biguanides (therapeutic use)
  • Clinical Trials as Topic
  • Dental Plaque (prevention & control)
  • Double-Blind Method
  • Drug Evaluation
  • Gingivitis (prevention & control)
  • Humans
  • Male
  • Middle Aged
  • Mouthwashes (therapeutic use)
  • Oral Hygiene
  • Placebos
  • Toothbrushing

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