[Effect of bile on the development of tumors of the stomach and small intestine induced in rats by N-methyl-N-nitro-N-nitrosoguanidine].

Abstract

The study of the influence of long-term injection of whole bile into rat's stomach on N-methyl-N-nitro-N-nitrosoguanidine-induced tumors revealed an increased frequency of stomach malignancies matched by a lower frequency of those in the small intestine as well as slower rates of growth of gastrointestinal tumors.

• Authors: N I Sherenesheva
• Journal: Voprosy onkologii (Vopr Onkol) Vol. 33 Issue 1 Pg. 83-9 ( 1987) ISSN: 0507-3758 [Print] Russia (Federation)
• Vernacular Title: Vliianie zhelchi na razvitie opukholeĭ zheludka i tonkoĭ kishki, indutsirovannykh u krys N-metil-N-nitro-N-nitrozoguanidinom.
• PMID: 3811314 (Publication Type: Comparative Study, English Abstract, Journal Article)

Chemical References

• Methylnitronitrosoguanidine

Topics

• Animals
• Bile (physiology)
• Intestinal Neoplasms (etiology, mortality, pathology)
• Intestine, Small (pathology)
• Male
• Methylnitronitrosoguanidine
• Rats
• Stomach Neoplasms (etiology, mortality, pathology)
• Time Factors