Abstract |
The study on sensitivity of clinical strains of the causative agents of purulent infections to carbenicillin showed that 34.6% of the staphylococcal strains, 48.1% of the E. coli strains and 40.3% of the Proteus strains were sensitive to the antibiotic. The strains of Ps. aeruginosa were characterized by moderate sensitivity to carbenicillin. The MTC for most of the isolates ranged within 25-128 microgram/ml. High therapeutic efficacy of carbenicillin in treatment of cases with purulent inflammatory processes of various localization was shown. Positive results were obtained in 82.5% of the adults and 76.2% of the premature infants treated with carbenicillin. A satisfactory therapeutic effect was observed in the cases with sepsis, diffuse purulent peritonitis and abscessing pneumonia treated with carbenicillin in combination with gentamicin.
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Authors | V P Pozdniakova, M A Petrova, A M Marshak, R V Makarenkova, I P Zamotaev |
Journal | Antibiotiki
(Antibiotiki)
Vol. 24
Issue 7
Pg. 526-31
(Jul 1979)
ISSN: 0003-5637 [Print] Russia (Federation) |
Vernacular Title | Klinicheskaia éffektivnost' karbenitsillina pri gnoĭno-vospalitel'-nykh protsessakh razlichnoĭ lokalizatsii. |
PMID | 380455
(Publication Type: Clinical Trial, Comparative Study, English Abstract, Journal Article)
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Chemical References |
- Gentamicins
- Ampicillin
- Carbenicillin
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Topics |
- Adult
- Ampicillin
(therapeutic use)
- Carbenicillin
(therapeutic use)
- Clinical Trials as Topic
- Drug Evaluation
- Drug Therapy, Combination
- Gentamicins
(therapeutic use)
- Humans
- Infant, Newborn
- Infant, Premature
- Infant, Premature, Diseases
(drug therapy)
- Inflammation
(drug therapy)
- Microbial Sensitivity Tests
- Suppuration
(drug therapy)
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