A case of malignant cystic endocrine tumor of the pancreas.

Abstract

A malignant pancreatic endocrine tumor with a cystic appearance in a 66-yr-old woman was reported. Total pancreatectomy was performed under the diagnosis of cystadenocarcinoma. The tumor was large and cystic, but the solid portion of the tumor showed histologically a ribbon-like array of small uniform cells typical for endocrine tumors. Immunohistochemically, most tumor cells were immunoreactive for neuron-specific enolase, chromogranin, and Leu 7-epitope. Ultrastructurally, innumerable neurosecretory granules were demonstrated in the cytoplasm of most tumor cells. The patient survived for 5.5 yr after operation despite liver metastases, some of which also showed cystic appearances.

• Authors: T Kamisawa, M Fukayama, M Koike, I Tabata, A Okamoto
• Journal: The American journal of gastroenterology (Am J Gastroenterol) Vol. 82 Issue 1 Pg. 86-9 (Jan 1987) ISSN: 0002-9270 [Print] United States
• PMID: 3799587 (Publication Type: Case Reports, Journal Article)

Topics

• Aged
• Cystadenocarcinoma (pathology, ultrastructure)
• Female
• Humans
• Pancreatic Neoplasms (pathology, ultrastructure)