| Abstract | From 1974 to 1976 Acute Amoebic Hepatic Abscess treatment was viewed retrospectively with a random double blind prospective study administering metronidazol emetine, or a combination of both to three groups of 20 patients per group. The retrospective study of 1974 underlines the then predominant tendency toward a surgical management with a higher mortality (p less than 0.002). In 1976 medical treatment patients increased with a corresponding diminution of mortality (p less than 0.001). The prospective study showed no statistically significant response difference to the pharmacologic treatment variations. Here only 1.6% of patients underwent surgery and 1/3 of them received puncture drainage due to medical treatment failure. We conclude that non complicated acute amoebic liver abscess treatment should be medical, preferably with only one antiamoebic drug. |
| Authors | A Esquivel López, G González Espínola, J R García Garduño, V Guarner Dalias |
| Journal | Revista de gastroenterología de México
(Rev Gastroenterol Mex)
1979 Apr-Jun
Vol. 44
Issue 2
Pg. 51-6
ISSN: 0375-0906 MEXICO |
| Vernacular Title | Algunas consideraciones en el tratamiento del absceso hepático amibiano. |
| PMID | 379955
(Publication Type: Clinical Trial, Comparative Study, English Abstract, Journal Article, Randomized Controlled Trial)
|
| Chemical References |
- Placebos
- Metronidazole
- Emetine
|
| Topics |
- Clinical Trials as Topic
- Double-Blind Method
- Drug Evaluation
- Emetine
(administration & dosage, therapeutic use)
- Humans
- Injections, Intramuscular
- Liver Abscess, Amebic
(drug therapy)
- Metronidazole
(administration & dosage, therapeutic use)
- Placebos
|
