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Hemodynamic effects of "san-huang-hsieh-hsin-tang" in patients with essential hypertension.

Abstract
The ancient Chinese formula of "San-Huang-Hsieh-Hsin-Tang" (S-T) was originally used for patients with "epigastric fullness, flushing, restlessness, constipation and a hard pulse" (Chang 115 B.C.). All these symptoms are frequently observed in patients with essential hypertension. We assessed the antihypertensive and hemodynamic effects of this formula, and found that S-T decreased blood pressure, total peripheral resistance, heart rate and cardiac contractile force. S-T had no apparent effects on cardiac output and blood volume.
AuthorsH C Chen, M T Hsieh
JournalThe American journal of Chinese medicine (Am J Chin Med) Vol. 14 Issue 3-4 Pg. 153-6 ( 1986) ISSN: 0192-415X [Print] Singapore
PMID3799532 (Publication Type: Journal Article, Research Support, Non-U.S. Gov't)
Chemical References
  • Antihypertensive Agents
  • Drugs, Chinese Herbal
  • Plant Extracts
  • san-huang-hsieh-hsin-tang
Topics
  • Adult
  • Antihypertensive Agents (adverse effects, pharmacology, therapeutic use)
  • Drugs, Chinese Herbal
  • Female
  • Hemodynamics (drug effects)
  • Humans
  • Hypertension (drug therapy, physiopathology)
  • Male
  • Medicine, Chinese Traditional
  • Medicine, East Asian Traditional
  • Plant Extracts
  • Plants, Medicinal

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