Single-dose gentamicin therapy of recurrent urinary tract infection in patients with normal urinary tracts.

Abstract

Results of single-dose therapy of urinary tract infections in pediatric patients have been contradictory mainly because of selection criteria. We evaluated the efficacy of a single dose of gentamicin in patients with normal urinary tracts and in whom urinary tract infections were recurrent. Twenty-one patients were included in the study, and a similar number in a conventional group given treatment for 10 days. Cure rate was 100% in both groups. The recurrence rates of 67% in the study and 52% in the conventional group were comparable. Single-dose therapy seems to have a role in the treatment of urinary tract infection in the absence of urinary tract malformation.

• Authors: A J Khan, K Kumar, H E Evans
• Journal: The Journal of pediatrics (J Pediatr) Vol. 110 Issue 1 Pg. 131-5 (Jan 1987) ISSN: 0022-3476 [Print] United States
• PMID: 3794874 (Publication Type: Clinical Trial, Controlled Clinical Trial, Journal Article)

Chemical References

• Gentamicins

Topics

• Adolescent
• Child
• Drug Administration Schedule
• Drug Evaluation
• Female
• Gentamicins (administration & dosage, therapeutic use)
• Humans
• Injections, Intramuscular
• Recurrence
• Urinary Tract (anatomy & histology)
• Urinary Tract Infections (drug therapy, microbiology)