An incidental finding of large cell calcifying Sertoli cell tumor in an orchidectomy specimen for a separate adenomatoid tumor.

Abstract

Introduction:

Large cell calcifying Sertoli cell tumors are exceedingly rare. They are most commonly benign, but risks for malignancy include older age, larger size of tumor, and solitary tumors. To the author's knowledge, this is the first case reported of an incidental large cell calcifying Sertoli cell tumor when an orchidectomy was performed for a separate lesion.

Case presentation:

A 31-year-old male presented with a painless testicular lump. Ultrasound demonstrated an exophytic lesion in the superolateral aspect and calcifications were noted inferomedially and inferolaterally in the right testis. On histology from radical orchidectomy, the superolateral lesion was found to be an adenomatoid tumor, and the calcifications inferiorly represented a large cell calcifying Sertoli cell tumor. The background showed foci of germ cell neoplasia in situ but no evidence of invasive malignancy.

Conclusion:

Calcifications on ultrasound in isolation may represent large cell calcifying Sertoli Cell tumors.

• Authors: Lauren Crone, Sophie C Prendergast, Nick Mayer, Frank O'Brien
• Journal: IJU case reports (IJU Case Rep) Vol. 6 Issue 6 Pg. 373-376 (Nov 2023) ISSN: 2577-171X [Electronic] Australia
• PMID: 37928287 (Publication Type: Case Reports)
• Copyright: © 2023 The Authors. IJU Case Reports published by John Wiley & Sons Australia, Ltd on behalf of Japanese Urological Association.