[Clinical and hemodynamic effects of medium-term treatment with muzolimine in subjects with essential arterial hypertension].

Abstract

The antihypertensive effects and haemodynamic changes after administration of 30 mg/die of muzolimine for 30 days in a group of patients with mild or moderate essential hypertension have been evaluated. Our findings showed a significant reduction of body weight, arterial blood pressure, systemic vascular resistance, plasma volume and small but significant increase of left ventricular ejection fraction. No relevant side effect have been observed.

• Authors: G Licata, R Scaglione, G Parrinello, G B Rini, N Asta
• Journal: Giornale italiano di cardiologia (G Ital Cardiol) Vol. 16 Issue 7 Pg. 583-5 (Jul 1986) ISSN: 0046-5968 [Print] Italy
• Vernacular Title: Effetti clinici ed emodinamici del trattamento a medio termine con muzolimina in soggetti con ipertensione arteriosa essenziale.
• PMID: 3781147 (Publication Type: English Abstract, Journal Article)

Chemical References

• Pyrazoles
• Muzolimine

Topics

• Adult
• Body Weight (drug effects)
• Female
• Hemodynamics (drug effects)
• Humans
• Hypertension (drug therapy)
• Male
• Middle Aged
• Muzolimine (therapeutic use)
• Pyrazoles (therapeutic use)
• Time Factors