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Two doses of triprolidine for treatment of allergic rhinitis.

Abstract
Two doses of triprolidine (2.5 mg t.i.d. and 1.25 mg t.i.d.) were compared with placebo in 32 patients suffering from allergic rhinitis. Triprolidine 2.5 mg t.i.d. was statistically significantly better than placebo (p less than 0.05) in reducing the symptoms of sneezing and eye irritation. Neither dose of triprolidine produced significant drowsiness during the second week of treatment.
AuthorsM G Britton, D W Empey, G C John, M Hodder, D T Hughes
JournalAnnals of allergy (Ann Allergy) Vol. 42 Issue 5 Pg. 330-2 (May 1979) ISSN: 0003-4738 [Print] United States
PMID378040 (Publication Type: Clinical Trial, Controlled Clinical Trial, Journal Article)
Chemical References
  • Pyridines
  • Triprolidine
Topics
  • Adolescent
  • Adult
  • Clinical Trials as Topic
  • Dose-Response Relationship, Drug
  • Double-Blind Method
  • Female
  • Humans
  • Male
  • Middle Aged
  • Pyridines (therapeutic use)
  • Rhinitis, Allergic, Seasonal (drug therapy)
  • Sleep Stages
  • Triprolidine (therapeutic use)

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