Abstract |
Two doses of triprolidine (2.5 mg t.i.d. and 1.25 mg t.i.d.) were compared with placebo in 32 patients suffering from allergic rhinitis. Triprolidine 2.5 mg t.i.d. was statistically significantly better than placebo (p less than 0.05) in reducing the symptoms of sneezing and eye irritation. Neither dose of triprolidine produced significant drowsiness during the second week of treatment.
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Authors | M G Britton, D W Empey, G C John, M Hodder, D T Hughes |
Journal | Annals of allergy
(Ann Allergy)
Vol. 42
Issue 5
Pg. 330-2
(May 1979)
ISSN: 0003-4738 [Print] United States |
PMID | 378040
(Publication Type: Clinical Trial, Controlled Clinical Trial, Journal Article)
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Chemical References |
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Topics |
- Adolescent
- Adult
- Clinical Trials as Topic
- Dose-Response Relationship, Drug
- Double-Blind Method
- Female
- Humans
- Male
- Middle Aged
- Pyridines
(therapeutic use)
- Rhinitis, Allergic, Seasonal
(drug therapy)
- Sleep Stages
- Triprolidine
(therapeutic use)
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