Comparison of the efficacy of oxygen-ozone and lidocaine injections in the treatment of myofascial pain syndrome: A randomized clinical trial.

Abstract

Objectives:

This study aims to compare effectiveness of oxygen-ozone injection versus lidocaine injection on the trigger point in the treatment of myofascial pain syndrome (MPS).

Patients and methods:

Between April 2021 and December 2021, a total of 46 patients with MPS (8 males, 38 females; mean age: 44.7±10.4 years; range, 25 to 65 years) were included. The patients were randomized to either ozone injection (n=23) or lidocaine injection (n=23) groups. All injections were administered once a week for three consecutive weeks. The primary outcome measure was the pain severity assessed by Visual Analog Scale (VAS). Secondary outcome measures were cervical lateral flexion range of motion (ROM), pain score (PS), and Neck Disability Index (NDI). The measurements were performed before the treatment, and at four and 12 weeks after treatment.

Results:

There was a significant effect of time for VAS, PS, and NDI scores in both groups. Compared to baseline versus Weeks 4 and 12, the VAS, PS, and NDI scores significantly decreased over time in both groups (p<0.001 for all). A significant group X time interaction was identified regarding the VAS scores. The mean difference in the VAS scores over time was significantly higher in the lidocaine group compared to the oxygen-ozone group (p=0.028).

Conclusion:

Oxygen-ozone and lidocaine injections of the trigger point can effectively improve pain and functional status. However, lidocaine injection appears to be superior in reducing pain compared to oxygen-ozone injection, but is not superior in improving function and PS.

• Authors: Nurdan Korkmaz, Merve Örücü Atar, Sinem Uyar Köylü, Sefa Gümrük Aslan, Özge Tezen, Serdar Kesikburun
• Journal: Turkish journal of physical medicine and rehabilitation (Turk J Phys Med Rehabil) Vol. 69 Issue 3 Pg. 294-302 (Sep 2023) ISSN: 2587-1250 [Electronic] Turkey
• PMID: 37674800 (Publication Type: Journal Article)
• Copyright: Copyright © 2023, Turkish Society of Physical Medicine and Rehabilitation.