Intravenous Ceftriaxone on an Outpatient Basis in the Treatment of Ocular Syphilis.

Abstract

PURPOSE:

The goal of this study is to describe the clinical and laboratory outcomes of patients with syphilitic uveitis treated with 2 g intravenous Ceftriaxone daily on an outpatient treatment basis for 14 days, in the setting of the COVID pandemic and lack of hospitalization availability.

METHODS:

This study included a review of the clinical records from patients from January 2020 to December 2021 and who were then followed for 6 months at the Research Laboratory of Infectious Diseases in Ophthalmology of the National Institute of Infectious Diseases Evandro Chagas (INI) FIOCRUZ, Rio de Janeiro, Brazil.

CONCLUSION:

This study showed that almost all of the 15 patients were well treated for ocular syphilis with Ceftriaxone without any signs of therapeutic failure with documented clinical improvement and satisfactory decreasing VDRL titers.

• Authors: Amanda Gomes E Silva, Leticia Alcântara Pedroso, Flavia Veiga Costa, Raissa de Moraes Perlingeiro, Priscila Peixoto de Castro Oliveira, Ana Luisa Biancardi Barreto, Andre Luiz Land Curi
• Journal: Ocular immunology and inflammation (Ocul Immunol Inflamm) Pg. 1-3 (Aug 15 2023) ISSN: 1744-5078 [Electronic] England
• PMID: 37582224 (Publication Type: Journal Article)