A preliminary study on the immunodiagnosis of paragonimiasis--the physico-chemical and immunological characteristics of the crude and partially purified antigens of Paragonimus westermani (Liaoning).

We have now succeeded in preparing a partially purified antigen (Fr. 1). The positive rates of the indirect ELISA were 100% both for sera of proved human cases and dogs infected with Paragonimus westermani when Fr. 1 was used, whereas the positive rates of the test were 71.4% and 75% on sera from patients and infected dogs respectively when crude antigen was used. Moreover, it is also better than the crude antigen in specificity, so a more reliable test in immunodiagnosis of paragonimiasis is available in our laboratory.
AuthorsX Y Zhang, J X Sun, J Xiong, L Y He, P Z Gao, H H Li, H L Zhong
JournalScientia Sinica. Series B, Chemical, biological, agricultural, medical & earth sciences / Chung-kuo k'o hsüeh yüan, chu pan (Sci Sin B) Vol. 29 Issue 1 Pg. 67-75 (Jan 1986) ISSN: 0253-5823 [Print] CHINA
PMID3749865 (Publication Type: Journal Article, Research Support, Non-U.S. Gov't)
Chemical References
  • Antigens, Helminth
  • Animals
  • Antigens, Helminth (immunology, isolation & purification)
  • Dogs
  • Enzyme-Linked Immunosorbent Assay
  • Humans
  • Paragonimiasis (diagnosis)
  • Paragonimus (immunology)

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