Abstract |
The concentration of 2,4,6-trichlorophenol was measured in the blood and various other tissues of the rat after IP administration of the compound at 25 mg per kg body weight. The highest concentration, 329 +/- 117 nmol X g-1, was found in the kidney. Half-times were between 1.4 and 1.8 h in the blood, brain, fat, kidney, liver and muscle. The extent of conjugation of 2,4,6-trichlorophenol was also investigated by measuring total and free chlorophenol in the blood.
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Authors | K Pekari, C Boudène, A Aitio |
Journal | Archives of toxicology
(Arch Toxicol)
Vol. 59
Issue 1
Pg. 41-4
(May 1986)
ISSN: 0340-5761 [Print] Germany |
PMID | 3741142
(Publication Type: Journal Article)
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Chemical References |
- Chlorophenols
- Glucuronates
- 2,4,6-trichlorophenol
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Topics |
- Animals
- Chlorophenols
(blood, metabolism)
- Chromatography, Gas
- Female
- Glucuronates
(metabolism)
- Kinetics
- Organ Size
- Organ Specificity
- Rats
- Rats, Inbred Strains
- Tissue Distribution
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