Abstract |
An increase in the aggregation properties of platelets accompanied by the activation of glycogenolysis and glycolysis was established in patients with unstable angina as compared to a control group of healthy persons. In most cases corinfar therapy resulted in a positive time course of the main platelet indices and a marked improvement of the patients' status. The correlation between the platelet aggregation index and phosphorylase A activity and their association with a course of disease indicated an opportunity of using these indices as accessory diagnostic criteria and control over therapeutic efficacy in unstable angina.
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Authors | I G Strizhak, K I Shanygina, N A Novikova, I N Chernysheva |
Journal | Terapevticheskii arkhiv
(Ter Arkh)
Vol. 58
Issue 5
Pg. 73-7
( 1986)
ISSN: 0040-3660 [Print] Russia (Federation) |
Vernacular Title | Vliianie korinfara na dinamicheskie funktsii i nekotorye pokazateli glikoliza i glikogenoliza trombotsitov u bol'nykh nestabil'noĭ stenokardieĭ. |
PMID | 3738797
(Publication Type: English Abstract, Journal Article)
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Chemical References |
- Glycogen
- Phosphorylase a
- Hexokinase
- Nifedipine
|
Topics |
- Adult
- Angina Pectoris
(blood)
- Angina, Unstable
(blood, drug therapy)
- Blood Platelets
(drug effects)
- Female
- Glycogen
(blood)
- Glycolysis
(drug effects)
- Hexokinase
(blood)
- Humans
- Male
- Middle Aged
- Nifedipine
(therapeutic use)
- Phosphorylase a
(blood)
- Platelet Adhesiveness
(drug effects)
- Platelet Aggregation
(drug effects)
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