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[Effect of corinfar on the dynamic function and various indices of glycolysis and glycogenolysis in the thrombocytes of patients with unstable stenocardia].

Abstract
An increase in the aggregation properties of platelets accompanied by the activation of glycogenolysis and glycolysis was established in patients with unstable angina as compared to a control group of healthy persons. In most cases corinfar therapy resulted in a positive time course of the main platelet indices and a marked improvement of the patients' status. The correlation between the platelet aggregation index and phosphorylase A activity and their association with a course of disease indicated an opportunity of using these indices as accessory diagnostic criteria and control over therapeutic efficacy in unstable angina.
AuthorsI G Strizhak, K I Shanygina, N A Novikova, I N Chernysheva
JournalTerapevticheskii arkhiv (Ter Arkh) Vol. 58 Issue 5 Pg. 73-7 ( 1986) ISSN: 0040-3660 [Print] Russia (Federation)
Vernacular TitleVliianie korinfara na dinamicheskie funktsii i nekotorye pokazateli glikoliza i glikogenoliza trombotsitov u bol'nykh nestabil'noĭ stenokardieĭ.
PMID3738797 (Publication Type: English Abstract, Journal Article)
Chemical References
  • Glycogen
  • Phosphorylase a
  • Hexokinase
  • Nifedipine
Topics
  • Adult
  • Angina Pectoris (blood)
  • Angina, Unstable (blood, drug therapy)
  • Blood Platelets (drug effects)
  • Female
  • Glycogen (blood)
  • Glycolysis (drug effects)
  • Hexokinase (blood)
  • Humans
  • Male
  • Middle Aged
  • Nifedipine (therapeutic use)
  • Phosphorylase a (blood)
  • Platelet Adhesiveness (drug effects)
  • Platelet Aggregation (drug effects)

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