Transfemoral transcatheter aortic valve replacement for pure native aortic regurgitation: one-year outcomes of a single-center study.

Abstract

BACKGROUND:

Evidence about safety and efficacy of transcatheter aortic valve replacement (TAVR) with the Venus A-Valve system (Venus Medtech, Hangzhou, China) remains limited for patients with pure native aortic regurgitation (PNAR).

OBJECTIVES:

The single-center study sought to report the one-year clinical outcomes of the Venus A-Valve in the treatment of PNAR.

METHODS:

This study was a retrospective analysis of prospectively collected data. Data was from all consecutive patients who had PNAR and underwent TAVR with the Venus A-Valve system at our center from July 2020 and June 2021. Procedural and clinical outcomes up to one year were analyzed using Valve Academic Research Consortium-2 criteria.

RESULTS:

A total of 45 consecutive patients with PNAR underwent transfemoral TAVR with the Venus A-Valve system. The Mean age was 73.5 ± 5.5 years and 26.7% were female. All the TAVR procedures were performed via transfemoral access. Implantations were successful in 44 cases (97.8%). Only one patient was converted to surgical aortic valve replacement. No patient died intraoperatively. No second valve was implanted. In-hospital mortality rate was 2.3%. The one-year all-cause mortality rate was 4.7% without cardiovascular related death. No patient had moderate or severe paravalvular leakage during follow-up. At one year, the mean pressure gradient was 8.8 ± 0.9 mmHg, and left ventricular ejection fraction increased to 61.5 ± 3.6%.

CONCLUSIONS:

This single-center study demonstrated the safety and efficacy of transfemoral TAVR with the Venus A-Valve in the treatment of patients with PNAR.

• Authors: Hua-Jie Zheng, Yong-Bo Cheng, Chao-Jun Yan, De-Qing Lin, San-Jiu Yu, Jun Li, Ping He, Wei Cheng
• Journal: BMC cardiovascular disorders (BMC Cardiovasc Disord) Vol. 23 Issue 1 Pg. 330 (06 29 2023) ISSN: 1471-2261 [Electronic] England
• PMID: 37386379 (Publication Type: Journal Article)
• Copyright: © 2023. The Author(s).

Topics

• Humans
• Female
• Aged
• Male
• Aortic Valve Insufficiency (diagnostic imaging, etiology, surgery)
• Transcatheter Aortic Valve Replacement (adverse effects)
• Retrospective Studies
• Stroke Volume
• Ventricular Function, Left