Abstract |
Biosynthesis of cantharidin in a blister beetle, Lytta polita, is effectively inhibited by 6-fluoromevalonate. Inhibition is attributed specifically to the fluorine substituent. Biochemical inhibition has not been demonstrated previously for an arthropod's defensive substance.
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Authors | J E Carrel, J P Doom, J P McCormick |
Journal | Experientia
(Experientia)
Vol. 42
Issue 7
Pg. 853-4
(Jul 15 1986)
ISSN: 0014-4754 [Print] Switzerland |
PMID | 3732495
(Publication Type: Journal Article, Research Support, U.S. Gov't, P.H.S.)
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Chemical References |
- 6-fluoromevalonolactone
- Cantharidin
- Mevalonic Acid
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Topics |
- Animals
- Cantharidin
(metabolism)
- Coleoptera
(drug effects, metabolism)
- Male
- Mevalonic Acid
(analogs & derivatives, metabolism, pharmacology)
- Reproduction
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