HOMEPRODUCTSCOMPANYCONTACTFAQResearchDictionaryPharmaSign Up FREE or Login

Cantharidin biosynthesis in a blister beetle: inhibition by 6-fluoromevalonate causes chemical disarmament.

Abstract
Biosynthesis of cantharidin in a blister beetle, Lytta polita, is effectively inhibited by 6-fluoromevalonate. Inhibition is attributed specifically to the fluorine substituent. Biochemical inhibition has not been demonstrated previously for an arthropod's defensive substance.
AuthorsJ E Carrel, J P Doom, J P McCormick
JournalExperientia (Experientia) Vol. 42 Issue 7 Pg. 853-4 (Jul 15 1986) ISSN: 0014-4754 [Print] Switzerland
PMID3732495 (Publication Type: Journal Article, Research Support, U.S. Gov't, P.H.S.)
Chemical References
  • 6-fluoromevalonolactone
  • Cantharidin
  • Mevalonic Acid
Topics
  • Animals
  • Cantharidin (metabolism)
  • Coleoptera (drug effects, metabolism)
  • Male
  • Mevalonic Acid (analogs & derivatives, metabolism, pharmacology)
  • Reproduction

Join CureHunter, for free Research Interface BASIC access!

Take advantage of free CureHunter research engine access to explore the best drug and treatment options for any disease. Find out why thousands of doctors, pharma researchers and patient activists around the world use CureHunter every day.
Realize the full power of the drug-disease research graph!


Choose Username:
Email:
Password:
Verify Password:
Enter Code Shown: