This article describes the case of a 21-year-old female habitual
contact lens wearer who complained of left
eye pain, redness, and decreased vision for one week. When a ring-shaped corneal infiltration indicative of an
Acanthamoeba infection was discovered, standard anti-amoebic topical
therapy with
polyhexamethylene biguanide and
chlorhexidine was commenced. However, her
keratitis worsened. At the same time, corneal scraping revealed no pathogens. An anterior chamber examination revealed a loss of corneal sensation, and a positive herpes simplex virus (HSV)
immunoglobulin G serology test indicated HSV
keratitis. She was eventually treated with oral anti-viral medication and recovered completely. Her case was unusual, as she had a history of
contact lens use, painful corneal ulceration, and the development of
Acanthamoeba keratitis-like corneal ring infiltration. This case also reinforces the various manifestations of HSV
keratitis, which lead to delayed diagnosis and treatment.