Abstract |
Keratoacanthoma is a benign tumor; however, it may cause massive destruction of normal tissue during its rapid growth phase. Intralesional 5-fluorouracil (5-FU) has been shown to be an effective treatment for keratoacanthoma. We have successfully treated five patients with large keratoacanthomas in difficult locations. There have been no recurrences during follow-up periods ranging from 18 to 45 months. Intralesional 5-FU may be ineffective for keratoacanthomas that are not rapidly proliferating.
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Authors | C M Parker, C W Hanke |
Journal | Journal of the American Academy of Dermatology
(J Am Acad Dermatol)
Vol. 14
Issue 5 Pt 1
Pg. 770-7
(May 1986)
ISSN: 0190-9622 [Print] United States |
PMID | 3711381
(Publication Type: Journal Article)
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Chemical References |
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Topics |
- Adult
- Aged
- Facial Dermatoses
(drug therapy)
- Fluorouracil
(administration & dosage, therapeutic use)
- Follow-Up Studies
- Humans
- Injections
- Keratoacanthoma
(drug therapy)
- Male
- Middle Aged
- Time Factors
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