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Participation of tumor killing factor in the antitumor effect of Sarcophaga lectin.

Abstract
Antibody against tumor-killing factor inhibited cytotoxic activities produced in vitro by mouse peritoneal macrophages and in vivo in the serum of tumor-bearing mice in response to Sarcophaga lectin. These results suggest that tumor-killing factor participates in the antitumor effect of Sarcophaga lectin.
AuthorsA Itoh, F Ohsawa, Y Ohkuma, S Natori
JournalFEBS letters (FEBS Lett) Vol. 201 Issue 1 Pg. 37-40 (May 26 1986) ISSN: 0014-5793 [Print] England
PMID3709806 (Publication Type: Journal Article)
Chemical References
  • 20kDa lectin protein, Sarcophaga
  • Glycoproteins
  • Immune Sera
  • Insect Proteins
  • Lectins
  • Lectins, C-Type
  • Tumor Necrosis Factor-alpha
Topics
  • Animals
  • Carcinoma, Ehrlich Tumor (immunology)
  • Cell Line
  • Cytotoxicity Tests, Immunologic
  • Cytotoxicity, Immunologic
  • Diptera
  • Glycoproteins (immunology)
  • Immune Sera (pharmacology)
  • Insect Proteins
  • Lectins (pharmacology, therapeutic use)
  • Lectins, C-Type
  • Macrophages (immunology)
  • Mice
  • Neoplasms, Experimental (drug therapy, immunology)
  • Sarcoma 180 (immunology)
  • Tumor Necrosis Factor-alpha

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