Electrocardiographic changes during microlaryngoscopy in practolol-pretreated patients under balanced anaesthesia.

Abstract

Electrocardiographic (ECG) changes were studied in 82 adult patients with a mean age of 49 years undergoing microlaryngoscopy. The patients were pretreated with practolol 0.15 mg/kg i.v. 5 min before induction of anaesthesia with thiopental. Anaesthesia was maintained with nitrous oxide in oxygen, fentanyl and suxamethonium-infusion. ECG changes occurred in 49% of the patients before anaesthesia and procedure. Pre-existing ECG changes increased or new changes occurred in 39% of the patients during intubation and in 38% during the procedure. The most common preanaesthetic ECG changes were flat or negative T-wave (18%), sinus tachycardia (13%), ischaemic S-T segment depression (8.5%) and intraventricular conduction disturbance (8.5%). ECG changes during intubation were sinus tachycardia (16%), ventricular ectopic beats (12%), supraventricular ectopic beats (10%) and ischaemic S-T segment depression (10%). The most common changes during microlaryngoscopy were supraventricular ectopic beats (16%), T-wave flattening or inversion (15%), ischaemic S-T segment depression (11%) and sinus bradycardia (10%). In all patients ECG changes disappeared without any special treatment. Unlike our earlier identical study without practolol pretreatment, neither sinus tachycardia nor junctional rhythm occurred during microlaryngoscopy in the present study. The results suggest that practolol pretreatment before microlaryngoscopy is especially useful when sinus tachycardia and junctional rhythm should be avoided.

• Authors: L Saarnivaara, E Kentala, U M Kautto, H Yrjölä
• Journal: Acta anaesthesiologica Scandinavica (Acta Anaesthesiol Scand) Vol. 30 Issue 2 Pg. 128-31 (Feb 1986) ISSN: 0001-5172 [Print] England
• PMID: 3705899 (Publication Type: Journal Article)

Chemical References

• Succinylcholine
• Thiopental
• Nitrous Oxide
• Practolol
• Fentanyl

Topics

• Adult
• Anesthesia, General (adverse effects)
• Arrhythmias, Cardiac (etiology, prevention & control)
• Electrocardiography
• Female
• Fentanyl
• Humans
• Intubation, Intratracheal
• Laryngoscopy (adverse effects)
• Male
• Middle Aged
• Nitrous Oxide
• Practolol (therapeutic use)
• Preanesthetic Medication
• Succinylcholine
• Thiopental