[Effect of physical loading on serum enzyme activity in post-myocardial infarct patients].

Abstract

The study of patterns of serum AST, ALT, CPK, LDH, and glycogen phosphorylase (GP) activity following bicycle ergometry in 26 male patients 1 to 1.5 months after myocardial infarction demonstrated no increase in AST, ALT and CPK activity, whereas total LDH activity was increased, with a tendency to elevated LDH-1 and LDH-2 fractions, as compared to the baseline, in those cases where exercise was discontinued because of ST depression. Patients with favorable response to bicycle ergometry that continued until the submaximum heart rate for a given age was achieved showed a tendency to elevated LDH-5 that may be a physiological response to exercise. The demonstrated increase in total GP activity, both in patients with exercise-induced ST depression and in those with elevated ST from the leads corresponding to the site of myocardial infarction, may reflect stress-induced reversible ischemia.

• Authors: A Zh Azhmukhanbetova, L F Nikolaeva, V N Titov, I K Filippov, S S Markarian
• Journal: Kardiologiia (Kardiologiia) Vol. 26 Issue 2 Pg. 61-7 (Feb 1986) ISSN: 0022-9040 [Print] Russia (Federation)
• Vernacular Title: Vliianie fizicheskoĭ nagruzki na aktivnost' fermentov v syvorotke krovi u bol'nykh, perenesshikh infarkt miokarda.
• PMID: 3702199 (Publication Type: English Abstract, Journal Article)

Chemical References

• Isoenzymes
• L-Lactate Dehydrogenase
• Phosphorylases
• Aspartate Aminotransferases
• Alanine Transaminase
• Creatine Kinase

Topics

• Adult
• Alanine Transaminase (blood)
• Aspartate Aminotransferases (blood)
• Creatine Kinase (blood)
• Electrocardiography
• Exercise Test
• Humans
• Isoenzymes
• L-Lactate Dehydrogenase (blood)
• Male
• Middle Aged
• Myocardial Infarction (enzymology, physiopathology)
• Phosphorylases (blood)