Abstract |
Diuresis by IV administration of 5% dextrose in a balanced electrolyte solution ( BES) reduced the frequency of occurrence of postmyelographic seizures in dogs. In the first study, a single myelogram was obtained in 8 dogs without dextrose diuresis. Two of these dogs weighed greater than 15 kg and both had seizures after metrizamide myelography. The remaining 6 dogs weighed less than 15 kg and only 2 had seizures. Greater body weight may have increased the risk of postmyelographic convulsions. In a crossover study, myelograms were obtained in 12 dogs weighing 20 to 31 kg. Six dogs were given 5% dextrose in BES (20 ml/kg of body weight/hr [diuresed]) and 6 were given BES alone (10 ml/kg/hr [not diuresed]). When myelography was repeated 10 days later, the 6 dogs that had been given 5% dextrose in BES were given BES only and the 6 dogs that had been given BES alone were given 5% dextrose in BES. The frequency of convulsions after metrizamide myelography was lower when dogs were given dextrose (33%) than when they were not (100%).
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Authors | P M Tamas, M A Walker, R R Paddleford, S R Tinkel |
Journal | Journal of the American Veterinary Medical Association
(J Am Vet Med Assoc)
Vol. 188
Issue 7
Pg. 710-2
(Apr 01 1986)
ISSN: 0003-1488 [Print] United States |
PMID | 3700226
(Publication Type: Journal Article)
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Chemical References |
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Topics |
- Animals
- Diuresis
(drug effects)
- Dog Diseases
(chemically induced, prevention & control)
- Dogs
- Female
- Glucose
(administration & dosage, therapeutic use)
- Male
- Metrizamide
(adverse effects)
- Myelography
(adverse effects, veterinary)
- Seizures
(chemically induced, prevention & control, veterinary)
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