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Bromcresol purple method for serum albumin gives falsely low values in patients with renal insufficiency.

Abstract
In patients with renal insufficiency, the BCP method underestimated the serum albumin. In non-renal patients, the BCP method gave albumin results in good agreement with the immunological method. The underestimation did not appear to be related to the degree of renal impairment. The interferent appears to act by preventing the binding of BCP to albumin. The BCG method is much less susceptible to this interference.
AuthorsG A Maguire, C P Price
JournalClinica chimica acta; international journal of clinical chemistry (Clin Chim Acta) Vol. 155 Issue 1 Pg. 83-7 (Feb 28 1986) ISSN: 0009-8981 [Print] Netherlands
PMID3698308 (Publication Type: Comparative Study, Journal Article)
Chemical References
  • Cresols
  • Serum Albumin
  • Bromcresol Purple
Topics
  • Bromcresol Purple
  • Cresols
  • False Negative Reactions
  • Humans
  • Immunoassay
  • Kidney Failure, Chronic (blood)
  • Nephelometry and Turbidimetry
  • Renal Dialysis
  • Serum Albumin (analysis)

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