[The course of renal function in vesicorenal reflux. Study using I-123 Hippuran].

Abstract

Fifty-two patients with vesicoureteral reflux (age: 6.4 +/- 6.2 years) were examined by IVP, voiding cystouretrography and 123 I-Hippuran studies. 17 patients were not operated; 26 had an antireflux, 9 an urethral surgery. The follow-up was 2 years for 39 of these patients, with at least one evaluation per year. The observations were: Unoperated patients were younger, had a lower radiological grade of reflux and renal functional impairment was less frequent. Functional impairment was initially equally distributed in unilateral (53%) and bilateral (54%) reflux. Radiological grade of reflux had an unsatisfactory predictive value for functional renal status. Functional renal status at 2 years was unchanged in 82% of patients. Improvement was observed in 8%, deterioration in 10%. These results were not influenced by the choice of treatment. However, reflux persistence was more frequently observed in the un-operated group (50% versus 5%). Renal transit times of 123 I-Hippuran did not correlate with the functional status or the radiological grade of reflux.

• Authors: J Simon, A Schoutens, M Thirion, C Schulman
• Journal: Journal d'urologie (J Urol (Paris)) Vol. 93 Issue 4 Pg. 187-91 ( 1987) ISSN: 0248-0018 [Print] France
• Vernacular Title: Evolution de la fonction rénale en présence de reflux vésico-rénal. Etude par l'123 I-Hippuran.
• PMID: 3680968 (Publication Type: English Abstract, Journal Article)

Chemical References

• Iodohippuric Acid

Topics

• Adolescent
• Child
• Child, Preschool
• Female
• Follow-Up Studies
• Humans
• Infant
• Iodohippuric Acid
• Kidney (physiopathology)
• Male
• Vesico-Ureteral Reflux (drug therapy, physiopathology, surgery)