Effects of intravitreal injection of fluorosilicone oil after vitrectomy in the rabbit eye.

Abstract

Because fluorosilicone oil is heavier than silicone oil, it may be superior in the therapy of proliferative vitreoretinopathy. To evaluate the ocular toxicity of fluorosilicone oil we performed pars plana lentectomy and vitrectomy on 14 rabbit eyes and injected approximately 1.5 mL of the oil (viscosity 10,000 centistoke) into the vitreous chamber of 10. No clinical or histologic evidence of toxic ocular effects was noted up to 2 months after the procedure.

• Authors: R Paylor, G A Peyman, S Badri
• Journal: Canadian journal of ophthalmology. Journal canadien d'ophtalmologie (Can J Ophthalmol) Vol. 22 Issue 5 Pg. 251-3 (Aug 1987) ISSN: 0008-4182 [Print] England
• PMID: 3664352 (Publication Type: Journal Article, Research Support, Non-U.S. Gov't, Research Support, U.S. Gov't, P.H.S.)

Chemical References

• Silicone Oils

Topics

• Animals
• Injections
• Rabbits
• Silicone Oils (toxicity)
• Vitrectomy
• Vitreous Body (drug effects)