Abstract | OBJECTIVE: PATIENTS: Twenty patients with unilateral sudden sensorineural hearing loss with an improvement of pure-tone average (PTA) less than 10 dB after primary systemic treatment with steroids. INTERVENTIONS: Delivery of DSP to the round window niche via saturated sponge gelatin for 2 weeks. MAIN OUTCOME MEASURES: Pure-tone audiometry was taken at the beginning and 4 to 8 weeks after the end of the salvage treatment. RESULTS: PTA thresholds were improved at least 10 dB in 11 of 20 patients (55%) by a mean value of 11.9 dB. The hearing threshold at 500, 1000, and 2000 Hz were improved after salvage treatment, but there was no significant change at 4000 Hz. The PTAs also recovered after the salvage treatment. CONCLUSIONS:
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Authors | Xia Lei, Xiao Yin, Lin Hu, Xiaodong Du, Changling Sun |
Journal | Otology & neurotology : official publication of the American Otological Society, American Neurotology Society [and] European Academy of Otology and Neurotology
(Otol Neurotol)
Vol. 44
Issue 2
Pg. e63-e67
(02 01 2023)
ISSN: 1537-4505 [Electronic] United States |
PMID | 36624588
(Publication Type: Journal Article)
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Copyright | Copyright © 2022, Otology & Neurotology, Inc. |
Chemical References |
- Gelatin
- Dexamethasone
- Glucocorticoids
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Topics |
- Humans
- Gelatin
(therapeutic use)
- Hearing Loss, Sensorineural
(drug therapy)
- Hearing
- Audiometry, Pure-Tone
- Dexamethasone
(therapeutic use)
- Treatment Outcome
- Hearing Loss, Sudden
(drug therapy)
- Glucocorticoids
(therapeutic use)
- Tympanic Membrane
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