[Study of clinical efficacy and safety of long-term cinoxacin therapy of chronic urogenital organ infection].

Abstract

Thirty-five patients with chronic simple and complicated urogenital organ infections were treated with 400 mg/day Cinoxacin for 60 to 284 days. The effects were judged according to improvements of subjective symptoms, bacteriuria and pyuria before and after the complete administration. Overall clinical efficacy in 35 cases with urogenital organ infections was estimated as excellent: 54%, good: 26%, poor: 17%, and effectiveness rate: 80%. The clinical effectiveness rate in 12 cases of chronic simple urinary tract infection was 100%, and in 14 cases of chronic complicated urinary tract infections was 64%, and in 6 cases of chronic prostatitis the rate of effectiveness was 83%. No recurrence was observed during the treatment. No side-effects or toxicity were seen. Accordingly long-term Cinoxacin therapy seems to be useful in preventing recurrence in chronic infections encountered in the department of urology.

• Authors: Y Hayashi, E Terao, I Yamasaki
• Journal: Hinyokika kiyo. Acta urologica Japonica (Hinyokika Kiyo) Vol. 33 Issue 5 Pg. 799-805 (May 1987) ISSN: 0018-1994 [Print] Japan
• PMID: 3661347 (Publication Type: English Abstract, Journal Article)

Chemical References

• Pyridazines
• Cinoxacin

Topics

• Adult
• Aged
• Chronic Disease
• Cinoxacin (therapeutic use)
• Drug Evaluation
• Female
• Humans
• Male
• Middle Aged
• Prostatitis (drug therapy)
• Pyelonephritis (drug therapy)
• Pyridazines (therapeutic use)
• Urinary Tract Infections (drug therapy)