Abstract | OBJECTIVE: To compare the effect of chewing sugar-free gum towards alleviating self-reported orthodontic treatment (OT) pain compared with conventional analgesic drugs (CADs). SEARCH SOURCES: An unrestricted search of indexed databases and manual searching was performed up to September 2021. DATA SELECTION: Randomised controlled trials (RCTs) comparing the impact of chewing gum and CADs on relieving self-reported orthodontic pain were included. DATA EXTRACTION: Data screening, extraction and risk of bias (RoB) assessment were performed by two authors. Meta-analyses were performed using a random-effects model. The quality of available evidence was assessed using the Grades of Recommendation, Assessment, Development and Evaluation approach. RESULTS: Nine RCTs were included. Eight RCTs used the Visual Analogue Scale for self-reported pain assessment, while one RCT used the Numeric Rating Scale. Five RCTs had a high RoB and four RCTs had a moderate RoB. Power analysis for sample size estimation was performed in six RCTs. Separate meta-analyses were performed by pooling quantitative data from five RCTs that compared self-reported orthodontic pain between chewing gum and ibuprofen groups for the following timepoints: baseline; immediately; 2 hours; 6 hours; bedtime; 24 hours; 2 days; 3 days; 5 days; and 7 days after the placement of orthodontic appliances. None of the timepoints individually indicated a difference in self-reported pain scores between chewing sugar-free gum and ibuprofen groups. The overall level of evidence was very low. CONCLUSION: Chewing sugar-free gum is a potentially useful alternative to CADs towards pain alleviation during fixed OT.
|
Authors | Luay Jabr, Maryam Altuhafy, Abdul Basir Barmak, Paul Emile Rossouw, Dimitrios Michelogiannakis |
Journal | Journal of orthodontics
(J Orthod)
Vol. 50
Issue 2
Pg. 215-228
(06 2023)
ISSN: 1465-3133 [Electronic] England |
PMID | 36550619
(Publication Type: Meta-Analysis, Systematic Review, Journal Article)
|
Chemical References |
- Ibuprofen
- Chewing Gum
- Analgesics
|
Topics |
- Humans
- Ibuprofen
(therapeutic use)
- Chewing Gum
- Analgesics
(therapeutic use)
- Pain
- Orthodontic Appliances, Fixed
|