Numerous factors have been involved in exercise-induced
acute kidney injury (EIAKI), such as using non-steroidal anti-inflammatory drugs following exercise and idiopathic
renal hypouricemia (IRHUC). IRHUC is an autosomal recessive inherited disorder characterized by impaired tubular
uric acid transfer, impaired reabsorption, and accelerated
uric acid secretion. Some IRHUC patients have been shown to have EIAKI. A 27-year-old police officer was admitted to the hospital due to
anorexia and a serum
creatinine level of 18 mg/dL, after a "tug-ofwar" game. After one dialysis sessions per day over five days, his
creatinine dropped to 1.3 mg/dL. Six months later, he developed bilateral
flank pain and red discoloration of urine, following a 300-meter chase of a convict, and his
creatinine level increased to 2.3 mg/dL, which was corrected with proper hydration alone. Recurrent
acute kidney injury can be due to hereditary
renal hypouricemia, which should be considered among differential diagnoses for patients. DOI: 10.52547/ijkd.6992.