Subjective and Objective Taste Change After Stapes Surgery Systematic Review and Meta-Analysis.

Abstract

INTRODUCTION:

Iatrogenic injury to the chorda tympani (CT) is a well recognized, although potentially underestimated, consequence of stapes surgery. This study aims to review the currently available literature to determine the incidence and prognosis of taste disturbances in these patients.

DATA SOURCES:

PubMed, Embase, and Cochrane Library databases.

METHODS:

Databases were searched according to the Preferred Reporting Items for Systematic Reviews and Meta-Analyses. Search terms included (chorda tympani OR gustatory OR taste OR chemosensory OR dysgeusia OR nervus intermedius) AND (ear surgery OR middle ear OR stapes OR stapedectomy OR stapedotomy). Patients with prospective data collection including preoperative data were further divided by methodology into "objective" and "subjective" assessments of taste dysfunction. A systematic review was performed for all included studies, with meta-analysis using a random-effects model was used for those with comparable methodology and patient populations.

RESULTS:

Initial search yielded 2,959 articles that were screened according to inclusion and exclusion criteria. Once duplicates were removed, seven studies were identified, representing 173 patients with subjective testing (all seven studies) and 146 with objective testing (five studies). Eighty of 173 patients (46.2%) noted a disturbance in taste at early follow-up, whereas as 26 of 173 (15.0%) noted long-term problems. Objective methodology and result reporting were heterogenous and not amenable to pooled meta-analysis for all studies included.

CONCLUSION:

Changes in taste occur relatively frequently after stapedectomy. Surgeons should continue to counsel prospective patients as to the risks of both short- and long-term taste disturbances.

• Authors: Daniel H Coelho, Seong Lee, Edward Yang, Matthew Carli
• Journal: Otology & neurotology : official publication of the American Otological Society, American Neurotology Society [and] European Academy of Otology and Neurotology (Otol Neurotol) Vol. 44 Issue 1 Pg. 10-15 (01 01 2023) ISSN: 1537-4505 [Electronic] United States
• PMID: 36373699 (Publication Type: Meta-Analysis, Systematic Review, Journal Article)
• Copyright: Copyright © 2022, Otology & Neurotology, Inc.

Topics

• Humans
• Stapes Surgery (adverse effects, methods)
• Dysgeusia (epidemiology, etiology)
• Chorda Tympani Nerve (injuries)
• Otologic Surgical Procedures (adverse effects)
• Stapes
• Taste