[Erythron in patients with polycythemia vera during treatment by erythrocytapheresis and bloodletting].

Abstract

An analysis of the results of determination of erythropoietin in the blood plasma of patients with polycythemia vera and data on the kinetics of erythroid cell proliferation led to a conclusion that erythrocytapheresis more than bloodletting stimulated the production of erythropoietin and the cell proliferative potential. Activation of regenerative processes probably determined by deinhibition of the normal clone of bone marrow erythroid cells, can account for the mechanism of a therapeutic effect of erythrocytapheresis in patients with polycythemia vera.

• Authors: V I Gudim, T G Sarycheva, V M Kotel'nikov, A L Melikian, V S Ivanova
• Journal: Terapevticheskii arkhiv (Ter Arkh) Vol. 59 Issue 6 Pg. 48-51 ( 1987) ISSN: 0040-3660 [Print] Russia (Federation)
• Vernacular Title: Eritron u bol'nykh istinnoĭ politsitemieĭ v protsesse lecheniia éritrotsitaferezom i krovospuskaniiami.
• PMID: 3629498 (Publication Type: English Abstract, Journal Article)

Topics

• Blood Component Removal
• Bloodletting
• Erythrocytes
• Erythropoiesis
• Humans
• Polycythemia Vera (blood, therapy)