Abstract |
In vitro studies were performed that used varying concentrations of onion extract added to cell cultures of an epidermoid carcinoma cell line derived from hamster buccal pouch carcinoma (HCPC-1). The studies demonstrated tumor growth inhibition beginning after 24 hours of incubation at an onion extract concentration of 25% and above in culture media. After 4 days and 10 days of incubation, there was a noted decrease in tumor proliferation. The plating efficiency for 24 hours was observed to produce a 54-89% inhibition in plating density. The results indicated here provide in vitro evidence of the inhibitory and cytotoxic activity on an oral carcinoma cell line.
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Authors | K Niukian, J Schwartz, G Shklar |
Journal | Nutrition and cancer
(Nutr Cancer)
Vol. 10
Issue 3
Pg. 137-44
( 1987)
ISSN: 0163-5581 [Print] United States |
PMID | 3628037
(Publication Type: Journal Article)
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Chemical References |
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Topics |
- Allium
- Animals
- Cell Division
(drug effects)
- Cell Line
- Cheek
- Cricetinae
- Kinetics
- Mouth Neoplasms
(pathology)
- Plant Extracts
(pharmacology)
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