Studies on satellite nucleoli in rat hepatocytes and Novikoff hepatoma cells.

Abstract

The present study was undertaken to provide information on the presence and frequency of satellite nucleoli in cells with increased nucleolar biosynthetic activity. The number of hepatocytes containing satellite nucleoli was analyzed in rat liver, regenerating liver 18 h after partial hepatectomy and in Novikoff hepatoma ascites cells. In comparison with hepatocytes of normal liver, the number of both stimulated hepatocytes and malignant hepatoma cells containing satellite nucleoli was significantly reduced. The results also indicated that whereas most satellite nucleoli contain protein C23, a smaller percentage contain protein B23.

• Authors: K Smetana, R L Ochs, R K Busch, L C Yeoman, H Busch
• Journal: Cell and tissue research (Cell Tissue Res) Vol. 249 Issue 1 Pg. 235-9 (Jul 1987) ISSN: 0302-766X [Print] Germany
• PMID: 3621293 (Publication Type: Journal Article, Research Support, Non-U.S. Gov't, Research Support, U.S. Gov't, P.H.S.)

Topics

• Animals
• Cell Nucleolus (ultrastructure)
• Liver (cytology, ultrastructure)
• Liver Neoplasms, Experimental (pathology, ultrastructure)
• Liver Regeneration
• Microscopy, Electron
• Microscopy, Fluorescence
• Rats