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Shikimic acid and quinic acid are not mutagenic in the Ames assay.

Abstract
Shikimic acid, reported to cause tumors in mice, and its close structural analog, quinic acid, both ubiquitous constituents of higher plants, were found not be be mutagenic in the Ames assay when tested with and without the rat liver microsomal activation system.
AuthorsL B Jacobsen, C L Richardson, H G Floss
JournalLloydia (Lloydia) 1978 Sep-Oct Vol. 41 Issue 5 Pg. 450-2 ISSN: 0024-5461 [Print] United States
PMID362106 (Publication Type: Journal Article, Research Support, U.S. Gov't, P.H.S.)
Chemical References
  • Mutagens
  • Quinic Acid
  • Shikimic Acid
Topics
  • Animals
  • In Vitro Techniques
  • Microsomes, Liver (physiology)
  • Mutagens
  • Quinic Acid (pharmacology)
  • Rats
  • Salmonella typhimurium (drug effects, genetics)
  • Shikimic Acid (pharmacology)

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