Abstract |
The efficacy of a single dose trimethoprim in the treatment of the dysuria/ pyuria syndrome in women was prospectively studied in an open, controlled and randomized trail. Of 90 women aged 18-60 years 68 had and 22 had not significant bacteriuria when the urine was cultured. The 42 women in the single-dose group received trimethoprim 400 mg once while the 48 in the multi-dose group received trimethoprim 200 mg X 2 for five days. One week after ended treatment 83% were cured in the single-dose group, and 85% in the multi-dose group. One relapse and six reinfections occurred in the single-dose group, no relapse and seven reinfections in the multi-dose group. Two patients in the single-dose group and eight in the multi-dose group reported adverse effects. A single dose of trimethoprim seems to be safe and effective in the treatment of acute dysuria/ pyuria syndrome in women.
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Authors | A Baerheim |
Journal | Scandinavian journal of primary health care
(Scand J Prim Health Care)
Vol. 5
Issue 2
Pg. 87-90
(May 1987)
ISSN: 0281-3432 [Print] United States |
PMID | 3616278
(Publication Type: Clinical Trial, Comparative Study, Journal Article, Randomized Controlled Trial)
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Chemical References |
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Topics |
- Acute Disease
- Adolescent
- Adult
- Female
- Humans
- Middle Aged
- Pyuria
(drug therapy)
- Random Allocation
- Recurrence
- Trimethoprim
(administration & dosage, adverse effects)
- Urinary Tract Infections
(drug therapy)
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