[Effect of chronic stimulation of the emotionogenic zones of the hypothalamus on the status of carbohydrate metabolism in the rabbit].

Abstract

In chronic experiments on rabbits receiving for 3 months low doses of cholesterol (60 mg per 1 kg of body weight daily), a repeated prolonged (2 h daily) intermittent stimulation of negative and positive emotive zones of the hypothalamus through implanted electrodes (eliciting avoidance and self-stimulation reactions correspondingly),--resulted in uniform disturbances of carbohydrate metabolism. There was a significant reduction of glucose tolerance in comparison with the control group of rabbits with implanted electrodes, as well as a gradual development of a slight, but stable neurogenic hyperglycemia. Simultaneously, in both experimental rabbits groups there were an equal increase of alimentary hypercholesterolemia and a development of persistent neurogenic arterial hypertension.

• Authors: N L Iastrebtsova, I P Azizov, T A Leontovich
• Journal: Zhurnal vysshei nervnoi deiatelnosti imeni I P Pavlova (Zh Vyssh Nerv Deiat Im I P Pavlova) 1987 Mar-Apr Vol. 37 Issue 2 Pg. 323-9 ISSN: 0044-4677 [Print] Russia (Federation)
• Vernacular Title: Vliianie khronicheskogo razdrazheniia émotsiogennykh zon gipotalamusa na sostoianie uglevodnogo obmena u krolikov.
• PMID: 3590977 (Publication Type: English Abstract, Journal Article)

Chemical References

• Blood Glucose
• Cholesterol

Topics

• Animals
• Blood Glucose (analysis)
• Blood Pressure
• Brain Mapping
• Chinchilla
• Cholesterol (blood)
• Diet, Atherogenic
• Emotions (physiology)
• Escape Reaction (physiology)
• Hypothalamus (physiology)
• Self Stimulation (physiology)