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A comparison of noxythiolin and povidone-iodine in experimentally induced peritoneal infection in mice.

Abstract
Noxythiolin (Noxyflex, Geistlich), given intraperitoneally as a 2.5 per cent solution, protected mice from the lethal effects of an intraperitoneal injection of Escherichia coli. Povidone-iodine (Pevidine, Berk), containing 0.075 per cent iodine, gave no protection.
AuthorsM K Browne, G B Leslie, R W Pfirrman
JournalThe British journal of surgery (Br J Surg) Vol. 65 Issue 9 Pg. 601-2 (Sep 1978) ISSN: 0007-1323 [Print] England
PMID359084 (Publication Type: Comparative Study, Journal Article)
Chemical References
  • Noxythiolin
  • Povidone-Iodine
  • Povidone
  • Thiourea
Topics
  • Animals
  • Escherichia coli
  • Injections, Intraperitoneal
  • Male
  • Mice
  • Noxythiolin (administration & dosage, therapeutic use)
  • Peritonitis (drug therapy, etiology)
  • Povidone (analogs & derivatives)
  • Povidone-Iodine (administration & dosage, therapeutic use)
  • Thiourea (analogs & derivatives)

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